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‘Genetic Marker’ Vaccines for Selected Zoonotic Diseases
There is a critical need for improved vaccines for zoonotic diseases of economic and public health applications, such as Rift Valley Fever (RVF) and Avian Influenza (AI).
In addition to safety, efficacy, and the ability to manufacture sufficient quantities of vaccine, FAZD Center investigators are using modern recombinant technologies to incorporate genetic “markers” into RVF and AI vaccines to make it possible to distinguish vaccinated livestock from infected livestock. In an outbreak, this property will prevent unnecessary slaughter of animals, and which causes further damage to the economy through trade restrictions while creating challenges to the capacity for carcass disposal.
Principal investigators:
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- Related publication: "A multiplexed immunoassay for detection of antibodies against avian influenza viru"
- Article: "Which Chicken is Stricken?"